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Psychedelics For example, Vancouver, Canada, recently decriminalized all drugs — including Psychedelic s. This doesn’t make them legal; it just removes the federal prosecution charges if caught in possession of these substances. There are only a few exceptions in specific municipalities or states where psychedelic drugs like psilocybin or LSD are considered legal or decriminalized. Upregulation of the 5-HT2A receptor was seen after hepatectomy in young mice, whereas this upregulation was absent in old mice, possibly reflecting regenerative impairment. Pretreating old mice with DOI prior to hepatectomy increased the weight of the liver remnant compared with untreated animals, significantly improved hepatocyte proliferation, and converted animal survival from 48% to 86%. Their results demonstrate that 5-HT2A receptor activation by DOI restores deficient regeneration of old livers. Furrer et al. also reported that old animals had characteristic changes of pseudocapillarization, with l...